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1

The impact of deuteration on natural and synthetic lipids: A neutron diffraction study

Luchini, Alessandra, Delhom, Robin, Demé, Bruno, Laux, Valérie, Moulin, Martine, Haertlein, Michael, Pichler, Harald, Strohmeier, Gernot A., Wacklin, Hanna, Fragneto, Giovanna

Journal:

Colloids and Surfaces B: Biointerfaces

Year:

2018

Language:

english

File:

PDF, 1.60 MB

english, 2018

2

Neutron structure of type-III antifreeze protein allows the reconstruction of AFP–ice interface

Eduardo I. Howard, Matthew P. Blakeley, Michael Haertlein, Isabelle Petit- Haertlein, Andre Mitschler, Stuart J. Fisher, Alexandra Cousido- Siah, Andrés G. Salvay, Alexandre Popov, Christoph Muller- D

Journal:

Journal of Molecular Recognition

Year:

2011

Language:

english

File:

PDF, 783 KB

english, 2011

3

X-rays and neutrons for the study of DNA structure, hydration, and transitions

Ingrid M. Parrot, Valerie Laux, Volker Urban, Michael Haertlein, V. Trevor Forsyth

Journal:

Physica B: Condensed Matter

Year:

2006

Language:

english

File:

PDF, 826 KB

english, 2006

4

Novel thieno[2,3-b]- and [3,4-b]pyrans as potassium channel openers. Thiophene systems—XVII

Jeffery B. Press, James J. McNally, Pauline J. Sanfilippo, Michael F. Addo, Deborah Loughney, Edward Giardino, Laurence B. Katz, Robert Falotico, Barbara J. Haertlein

Journal:

Bioorganic & Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.77 MB

english, 1993

5

Solvent isotope effect on macromolecular dynamics inE. coli

Marion Jasnin, Moeava Tehei, Martine Moulin, Michael Haertlein, Giuseppe Zaccai

Journal:

European Biophysics Journal

Year:

2008

Language:

english

File:

PDF, 298 KB

english, 2008

6

Selective deuteration of tryptophan and methionine residues in maltose binding protein: a model system for neutron scattering

Valerie Laux, Phil Callow, Dmitri I. Svergun, Peter A. Timmins, V. Trevor Forsyth, Michael Haertlein

Journal:

European Biophysics Journal

Year:

2008

Language:

english

File:

PDF, 522 KB

english, 2008

7

Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042

William J. Hoekstra, Bruce E. Maryanoff, Patricia Andrade-Gordon, Judith H. Cohen, Michael J. Costanzo, Bruce P. Damiano, Barbara J. Haertlein, Bruce D. Harris, Jack A. Kauffman, Patricia M. Keane, Da

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 343 KB

english, 1996

8

Down to atomic-scale intracellular water dynamics

Jasnin, Marion, Moulin, Martine, Haertlein, Michael, Zaccai, Giuseppe, Tehei, Moeava

Journal:

Year:

2008

File:

PDF, 42 KB

2008

9

Down to atomic-scale intracellular water dynamics

Jasnin, Marion, Moulin, Martina, Haertlein, Michael, Zaccai, Giuseppe, Tehei, Moeava

Journal:

The EMBO Journal

Year:

2008

Language:

english

File:

PDF, 159 KB

english, 2008

10

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Rochel, Natacha, Ciesielski, Fabrice, Godet, Julien, Moman, Edelmiro, Roessle, Manfred, Peluso-Iltis, Carole, Moulin, Martine, Haertlein, Michael, Callow, Phil, Mély, Yves

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.54 MB

english, 2011

11

Vibrational Collective Dynamics of Dry Proteins in the Terahertz Region

Paciaroni, Alessandro, Orecchini, Andrea, Haertlein, Michael, Moulin, Martine, Conti Nibali, Valeria, De Francesco, Alessio, Petrillo, Caterina, Sacchetti, Francesco

Journal:

Journal of Physical Chemistry B

Year:

2012

Language:

english

File:

PDF, 483 KB

english, 2012

12

Expression, purification, assay, and crystal structure of perdeuterated human arginase I

Luigi Di Costanzo, Martine Moulin, Michael Haertlein, Flora Meilleur, David W. Christianson

Journal:

Archives of Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 1.36 MB

english, 2007

13

Corrigendum to “Deciphering Membrane Insertion of the Diphtheria Toxin T Domain by Specular Neutron Reflectometry and Solid-State NMR Spectroscopy” [J. Mol. Biol. (2009) 391, 872–883]

Alexandre Chenal, Lydia Prongidi-Fix, Aurélie Perier, Christopher Aisenbrey, Grégory Vernier, Stephan Lambotte, Michael Haertlein, Marie-Thérèse Dauvergne, Giovanna Fragneto, Burkhard Bechinger, Danie

Journal:

Journal of Molecular Biology

Year:

2009

File:

PDF, 88 KB

2009

14

A Hybrid Structural Model of the Complete Brugia malayi Cytoplasmic Asparaginyl-tRNA Synthetase

Thibaut Crepin, Francis Peterson, Michael Haertlein, Davin Jensen, Cheng Wang, Stephen Cusack, Michael Kron

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 2.79 MB

english, 2011

15

Do tissue levels of autoantigenic aminoacyl-tRNA synthetase predict clinical disease?

Michael A. Kron, Michael Petridis, Michael Haertlein, Bernadette Libranda-Ramirez, Linda E. Scaffidi

Journal:

Medical Hypotheses

Year:

2005

Language:

english

File:

PDF, 163 KB

english, 2005

16

Protein Surface and Core Dynamics Show Concerted Hydration-Dependent Activation

Wood, Kathleen, Gallat, François-Xavier, Otten, Renee, van Heel, Auke J., Lethier, Mathilde, van Eijck, Lambert, Moulin, Martine, Haertlein, Michael, Weik, Martin, Mulder, Frans A. A.

Journal:

Angewandte Chemie

Year:

2013

Language:

english

File:

PDF, 596 KB

english, 2013

17

Protein Surface and Core Dynamics Show Concerted Hydration-Dependent Activation

Wood, Kathleen, Gallat, François-Xavier, Otten, Renee, van Heel, Auke J., Lethier, Mathilde, van Eijck, Lambert, Moulin, Martine, Haertlein, Michael, Weik, Martin, Mulder, Frans A. A.

Journal:

Angewandte Chemie International Edition

Year:

2013

Language:

english

File:

PDF, 620 KB

english, 2013

18

Bilayer-Mediated Clustering and Functional Interaction of MscL Channels

Grage, Stephan L., Keleshian, Asbed M., Turdzeladze, Tamta, Battle, Andrew R., Tay, Wee C., May, Roland P., Holt, Stephen A., Contera, Sonia Antoranz, Haertlein, Michael, Moulin, Martine, Pal, Prithwi

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 1.90 MB

english, 2011

19

A neutron reflection study of adsorbed deuterated myoglobin layers on hydrophobic surfaces

Brouette, Nicolas, Fragneto, Giovanna, Cousin, Fabrice, Moulin, Martine, Haertlein, Michael, Sferrazza, Michele

Journal:

Journal of Colloid and Interface Science

Year:

2013

Language:

english

File:

PDF, 496 KB

english, 2013

20

Potent, Orally Active GPIIb/IIIa Antagonists Containing a Nipecotic Acid Subunit. Structure−Activity Studies Leading to the Discovery of RWJ-53308

Hoekstra, William J., Maryanoff, Bruce E., Damiano, Bruce P., Andrade-Gordon, Patricia, Cohen, Judith H., Costanzo, Michael J., Haertlein, Barbara J., Hecker, Leonard R., Hulshizer, Becky L., Kauffman

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

21

Interfacial Structure of Immobilized Antibodies and Perdeuterated HSA in Model Pregnancy Tests Measured with Neutron Reflectivity

Cowsill, Benjamin J., Zhao, Xiubo, Waigh, Thomas A., Eapen, Saji, Davies, Robert, Laux, Valerie, Haertlein, Michael, Forsyth, V. Trevor, Lu, Jian R.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

22

Clustering and Functional Interaction of MscL Channels

Keleshian, Asbed M., Grage, Stephan L., Turdzeladze, Tamta, Battle, Andrew R., Tay, Wee C., Holt, Stephen A., Contera, Sonia Antoranz, Haertlein, Michael, Moulin, Martine, Pal, Prithwish, Rohde, Paul

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

23

Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa

Giardino, Edward C, Haertlein, Barbara J, de Garavilla, Lawrence, Costanzo, Michael J, Damiano, Bruce P, Andrade-Gordon, Patricia, Maryanoff, Bruce E

Journal:

Blood Coagulation & Fibrinolysis

Year:

2010

Language:

english

File:

PDF, 401 KB

english, 2010

24

Intrinsic disorder within the erythrocyte binding-like proteins from Plasmodium falciparum

Blanc, Manuel, Coetzer, Theresa L., Blackledge, Martin, Haertlein, Michael, Mitchell, Edward P., Forsyth, V. Trevor, Jensen, Malene Ringkjøbing

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2014

Language:

english

File:

PDF, 3.06 MB

english, 2014

25

Adsorption of α-Synuclein to Supported Lipid Bilayers: Positioning and Role of Electrostatics

Hellstrand, Erik, Grey, Marie, Ainalem, Marie-Louise, Ankner, John, Forsyth, V. Trevor, Fragneto, Giovanna, Haertlein, Michael, Dauvergne, Marie-Therese, Nilsson, Hanna, Brundin, Patrik, Linse, Sara,

Journal:

ACS Chemical Neuroscience

Year:

2013

Language:

english

File:

PDF, 3.67 MB

english, 2013

26

Neutron Reflectometry Elucidates Density Profiles of Deuterated Proteins Adsorbed onto Surfaces Displaying Poly(ethylene glycol) Brushes: Evidence for Primary Adsorption

Schneck, Emanuel, Schollier, Audrey, Halperin, Avraham, Moulin, Martine, Haertlein, Michael, Sferrazza, Michele, Fragneto, Giovanna

Journal:

Year:

2013

Language:

english

File:

PDF, 3.31 MB

english, 2013

27

Dual Inhibition of Cathepsin G and Chymase Is Effective in Animal Models of Pulmonary Inflammation

Maryanoff, Bruce E., de Garavilla, Lawrence, Greco, Michael N., Haertlein, Barbara J., Wells, Grace I., Andrade-Gordon, Patricia, Abraham, William M.

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 170 KB

english, 2010

28

[IEEE 2010 International Conference on Nanoscience and Nanotechnology (ICONN) - Sydney, Australia (2010.02.22-2010.02.26)] 2010 International Conference on Nanoscience and Nanotechnology - Nanostructure of the "protein-nanoparticle corona" an indicator of toxicity?

White, John W., Lin, Jhih-Min, Ang, Joo Chuan, Campbell, Richard A., Laux, Valerie, Haertlein, Michael, Fragneto, Giovanna

Year:

2010

Language:

english

File:

PDF, 1.59 MB

english, 2010

29

Dynamical properties of the hydration shell of fully deuterated myoglobin

Achterhold, Klaus, Ostermann, Andreas, Moulin, Martine, Haertlein, Michael, Unruh, Tobias, Parak, Fritz G.

Journal:

Physical Review E

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

30

Vibrational dynamics changes of protein hydration water across the dynamic transition

Paciaroni, Alessandro, Orecchini, Andrea, Sebastiani, Federico, Capaccioli, Simone, Ngai, Kia L., Moulin, Martine, Haertlein, Michael, Petrillo, Caterina, Sacchetti, Francesco

Journal:

Journal of Non-Crystalline Solids

Year:

2015

Language:

english

File:

PDF, 667 KB

english, 2015

31

Effect of crowding on the conformation of interwound DNA strands from neutron scattering measurements and Monte Carlo simulations

Zhu, Xiaoying, Ng, Siow Yee, Gupta, Amar Nath, Feng, Yuan Ping, Ho, Bow, Lapp, Alain, Egelhaaf, Stefan U., Forsyth, V. Trevor, Haertlein, Michael, Moulin, Martine, Schweins, Ralf, van der Maarel, Joha

Journal:

Physical Review E

Year:

2010

Language:

english

File:

PDF, 253 KB

english, 2010

32

Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modifiedEscherichia coli

Maric, Selma, Thygesen, Mikkel B., Schiller, Jürgen, Marek, Magdalena, Moulin, Martine, Haertlein, Michael, Forsyth, V. Trevor, Bogdanov, Mikhail, Dowhan, William, Arleth, Lise, Pomorski, Thomas Günth

Journal:

Applied Microbiology and Biotechnology

Year:

2015

Language:

english

File:

PDF, 875 KB

english, 2015

33

Production and Analysis of Perdeuterated Lipids from Pichia pastoris Cells

de Ghellinck, Alexis, Schaller, Hubert, Laux, Valérie, Haertlein, Michael, Sferrazza, Michele, Maréchal, Eric, Wacklin, Hanna, Jouhet, Juliette, Fragneto, Giovanna, Witt, Stephan Neil

Journal:

Year:

2014

Language:

english

File:

PDF, 685 KB

english, 2014

34

The aggregation of “native” human serum albumin

White, John, Heß, David, Raynes, Jared, Laux, Valerie, Haertlein, Michael, Forsyth, Trevor, Jeyasingham, Anithahini

Journal:

European Biophysics Journal

Year:

2015

Language:

english

File:

PDF, 621 KB

english, 2015

35

Lipid polyunsaturation determines the extent of membrane structural changes induced by Amphotericin B in Pichia pastoris yeast

de Ghellinck, Alexis, Fragneto, Giovanna, Laux, Valerie, Haertlein, Michael, Jouhet, Juliette, Sferrazza, Michele, Wacklin, Hanna

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2015

Language:

english

File:

PDF, 1.52 MB

english, 2015

36

Multi-lamellar organization of fully deuterated lipid extracts of yeast membranes

Gerelli, Yuri, de Ghellinck, Alexis, Jouhet, Juliette, Laux, Valérie, Haertlein, Michael, Fragneto, Giovanna

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2014

Language:

english

File:

PDF, 762 KB

english, 2014

37

Conserved structure and domain organization among bacterial Slc26 transporters

Compton, Emma L. R., Page, Kimberly, Findlay, Heather E., Haertlein, Michael, Moulin, Martine, Zachariae, Ulrich, Norman, David G., Gabel, Frank, Javelle, Arnaud

Journal:

Biochemical Journal

Year:

2014

Language:

english

File:

PDF, 2.14 MB

english, 2014

38

Neutron reflection study of the interaction of the eukaryotic pore-forming actinoporin equinatoxin II with lipid membranes reveals intermediate states in pore formation

Wacklin, Hanna P., Bremec, Biserka Bakrač, Moulin, Martina, Rojko, Nejc, Haertlein, Michael, Forsyth, Trevor, Anderluh, Gregor, Norton, Raymond S.

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

39

Grafted biomembranes containing membrane proteins – the case of the leucine transporter

Jagalski, Vivien, Barker, Robert D., Thygesen, Mikkel B., Gotfryd, Kamil, Krüger, Mie B., Shi, Lei, Maric, Selma, Bovet, Nicolas, Moulin, Martine, Haertlein, Michael, Günther Pomorski, Thomas, Loland,

Journal:

Year:

2015

Language:

english

File:

PDF, 1.95 MB

english, 2015

40

Human CD4 metastability is a function of the allosteric disulfide bond in domain 2

Owen, Gavin Ray, Channell, Jennifer Anne, Forsyth, Trevor V, Haertlein, Michael, Mitchell, Edward P, Capovilla, Alexio, Papathanasopoulos, Maria, Cerutti, Nichole Michelle

Journal:

Year:

2016

Language:

english

File:

PDF, 2.92 MB

english, 2016

41

Stealth carriers for low-resolution structure determination of membrane proteins in solution

Maric, Selma, Skar-Gislinge, Nicholas, Midtgaard, Søren, Thygesen, Mikkel B., Schiller, Jürgen, Frielinghaus, Henrich, Moulin, Martine, Haertlein, Michael, Forsyth, V. Trevor, Pomorski, Thomas Günther

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2014

Language:

english

File:

PDF, 1.14 MB

english, 2014

42

Water Collective Dynamics in Whole Photosynthetic Green Algae as Affected by Protein Single Mutation

Russo, Daniela, Rea, Giuseppina, Lambreva, Maya D., Haertlein, Michael, Moulin, Martine, De Francesco, Alessio, Campi, Gaetano

Journal:

The Journal of Physical Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

43

Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses

Yee, Ai Woon, Moulin, Martine, Breteau, Nina, Haertlein, Michael, Mitchell, Edward P., Cooper, Jonathan B., Boeri Erba, Elisabetta, Forsyth, V. Trevor

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 2.02 MB

english, 2016

44

Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses

Yee, Ai Woon, Moulin, Martine, Breteau, Nina, Haertlein, Michael, Mitchell, Edward P., Cooper, Jonathan B., Boeri Erba, Elisabetta, Forsyth, V. Trevor

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 2.09 MB

english, 2016

45

Macromolecular structure phasing by neutron anomalous diffraction

Cuypers, Maxime G., Mason, Sax A., Mossou, Estelle, Haertlein, Michael, Forsyth, V. Trevor, Mitchell, Edward P.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 846 KB

english, 2016

46

Neutrons describe ectoine effects on water H-bonding and hydration around a soluble protein and a cell membrane

Zaccai, Giuseppe, Bagyan, Irina, Combet, Jérôme, Cuello, Gabriel J., Demé, Bruno, Fichou, Yann, Gallat, François-Xavier, Galvan Josa, Victor M., von Gronau, Susanne, Haertlein, Michael, Martel, Anne,

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.13 MB

english, 2016

47

Water Dynamics in Shewanella oneidensis at Ambient and High Pressure using Quasi-Elastic Neutron Scattering

Foglia, Fabrizia, Hazael, Rachael, Simeoni, Giovanna G., Appavou, Marie-Sousai, Moulin, Martine, Haertlein, Michael, Trevor Forsyth, V., Seydel, Tilo, Daniel, Isabelle, Meersman, Filip, McMillan, Paul

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

48

Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine

Waldie, Sarah, Lind, Tania K., Browning, Kathryn, Moulin, Martine, Haertlein, Michael, Forsyth, V. Trevor, Luchini, Alessandra, Strohmeier, Gernot A., Pichler, Harald, Maric, Selma, Cárdenas, Marité

Journal:

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

49

Deuterium effects on human serum albumin in solution

White, John, Laux, Valerie, Fraser, Nick, Heß, David, Haertlein, Michael, Forsyth, Trevor

Journal:

Physica B: Condensed Matter

Year:

2018

Language:

english

File:

PDF, 676 KB

english, 2018

50

Adsorption of Denaturated Lysozyme at the Air–Water Interface: Structure and Morphology

Campbell, Richard A., Tummino, Andrea, Varga, Imre, Milyaeva, Olga Yu., Krycki, Michael M., Lin, Shi-Yow, Laux, Valerie, Haertlein, Michael, Forsyth, Victor Trevor, Noskov, Boris A.

Journal:

Year:

2018

Language:

english

File:

PDF, 8.36 MB

english, 2018